What programs you have to use to produce good results?For that,I always use these combination
(there are also combination of websites I used):

fireworks+sketch up=3d model**

fireworks+premiere=video**

fireworks+flash=presentation

facebook+youtube=more viewers

facebook+twitter=social combo

Gmail+Yahoo mail=double mail storage

fireworks+movie maker+premiere=video

fireworks+renpy=visual novel game

fireworks+game maker=game

fireworks+RPG maker XP=RPG game

fireworks+flash+premiere=video

facebook+youtube+blog=more viewers,friends and fans

fireworks+sketch up=picture

fireworks+flash=animation

fireworks+flash=game

fireworks=picture

Icons Source:
www.iconspedia.com